DescriptionAir- and moisture-tolerant, this (+)-PSI Reagent was developed in theBaran lab for stereocontrolled synthesis of phosphorothioate oligonucleotides. The enantiomer, (−)-PSI Reagent, is also available (cat#ALD00602).The PSI Reagents open access to thiophosphate-based nucleotide molecules with therapeutic promise as demonstrated by theBaranlab in the preparation of pure stereoisomers of cyclic dinucleotides (CDNs) and antisense oligonucleotides (ASOs).
- Properties
- Weights
- Citation
| Name | (+)-PSI Reagent |
|---|---|
| CasNumber | 2245335-71-9 |
| GradePurity | ≥95% |
| Formula | C16H16F5OPS3 |
| MolecularWeight | 446.46 |
| IupacName | |
| Smiles | CC(=C)C1CCC2(C(C1)OP(=S)(S2)SC3=C(C(=C(C(=C3F)F)F)F)F)C |
| InchiKey | YPYCUYPOHPPYAS-DWBMIXFYSA-N |
| Inchi | 1S/C16H16F5OPS3/c1-7(2)8-4-5-16(3)9(6-8)22-23(24,26-16)25-15-13(20)11(18)10(17)12(19)14(15)21/h8-9H,1,4-6H2,2-3H3/t8-,9+,16+,23?/m0/s1 |
| Synonyms | (2R,3aR,6S,7aR)-3a-Methyl-2-((perfluorophenyl)thio)-6-(prop-1-en-2-yl)hexahydrobenzo[d][1,3,2]oxathi... |
| CidNumber |
| SKU | Size | Unit | Price $ | Stock | |
|---|---|---|---|---|---|
| P467207-100mg | 100 | mg | 103 | 2 | |
| P467207-500mg | 500 | mg | 308 | 1 | |
| P467207-1g | 1 | g | 515 | 1 |
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