L-α-Aminoadipic acid, a gliotoxic analogue of glutamate, has been shown to competitively inhibit the transport protein of D-[3H]-aspartate. Experiments have reported that this compound also causes a reduction in ischemic glutamate release in murine hippocampal slices in vitro. Additional research suggests that L-α-Aminoadipic acid inhibits astrocyte culture Kynurenic acid synthesis which demonstrates the ability to modulate neuronal degeneration. L-α-Aminoadipic acid is a inhibitor of GluR and Gl Syn.An inhibitor of ischemic glutamate release
- Properties
- Weights
- Citation
| Name | L-α-Aminoadipic acid |
|---|---|
| CasNumber | 1118-90-7 |
| GradePurity | ≥98% |
| Formula | C6H11NO4 |
| MolecularWeight | 161.16 |
| IupacName | |
| Smiles | C(CC(C(=O)O)N)CC(=O)O |
| InchiKey | OYIFNHCXNCRBQI-BYPYZUCNSA-N |
| Inchi | 1S/C6H11NO4/c7-4(6(10)11)2-1-3-5(8)9/h4H,1-3,7H2,(H,8,9)(H,10,11)/t4-/m0/s1 |
| Synonyms | L-2-Aminoadipic Acid | (S)-2-Aminohexanedioic Acid | L-Homoglutamic acid |
| CidNumber |
| SKU | Size | Unit | Price $ | Stock | |
|---|---|---|---|---|---|
| A100535-5g | 5 | g | 44 | 3 | |
| A100535-1g | 1 | g | 10 | 10 | |
| A100535-25g | 25 | g | 218 | 4 |
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