(+)-Penbutolol is a β-adrenoceptor antagonist, with an IC 50 of 0.74 μM (+)-Penbutolol is an optical isomer of l-penbutolol with Na + channel-blocking action .In Vitro(+)-penbutolol on the [Ca 2+ ] i -increase induced by LPC is concentration-dependent. (+)-penbutolol inhibits the rounding of cells dose dependently (8±4%, 56±4% and 66±2% at the concentrations of 10 -6 M, 5×10 -6 M and 10 -5 M, respectively). MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:IC50: 0.74 μM (β-adrenoceptor)
- Properties
- Weights
- Citation
| Name | (+)-Penbutolol |
|---|---|
| CasNumber | 38363-41-6 |
| GradePurity | ≥95% |
| Formula | C18H29NO2 |
| MolecularWeight | 291.43 |
| IupacName | |
| Smiles | CC(C)(C)NCC(COC1=CC=CC=C1C2CCCC2)O |
| InchiKey | KQXKVJAGOJTNJS-OAHLLOKOSA-N |
| Inchi | 1S/C18H29NO2/c1-18(2,3)19-12-15(20)13-21-17-11-7-6-10-16(17)14-8-4-5-9-14/h6-7,10-11,14-15,19-20H,4-5,8-9,12-13H2,1-3H3/t15-/m1/s1 |
| Synonyms | CCRIS 2854 | HY-116790A | KQXKVJAGOJTNJS-OAHLLOKOSA-N | MS-24164 | (+)-Isopenbutolol | 2-Propanol, 1... |
| CidNumber |
| SKU | Size | Unit | Price $ | Stock | |
|---|---|---|---|---|---|
| P651513-50mg | 50 | mg | 1501 | 1000 | |
| P651513-10mg | 10 | mg | 481 | 1000 | |
| P651513-100mg | 100 | mg | 2401 | 1000 | |
| P656706-1ml | 1 | ml | 331 | 1000 | |
| P651513-5mg | 5 | mg | 301 | 1000 |
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![((1R,3s,5S)-Bicyclo[3.3.1]nonan-3-yl)methyl ((S)-4-Methyl-1-oxo-1-(((S)-1-oxo-3-((S)-2-oxopyrrolidin-3-yl)propan-2-yl)amino)pentan-2-yl)carbamate](/image/getimage/bc0d2c13-9af1-4141-8982-d496c1c0aded "((1R,3s,5S)-Bicyclo[3.3.1]nonan-3-yl)methyl ((S)-4-Methyl-1-oxo-1-(((S)-1-oxo-3-((S)-2-oxopyrrolidin-3-yl)propan-2-yl)amino)pentan-2-yl)carbamate")
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